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Home->Biomarker and Proteomics Services Enhanced Pathway, Biomarker Discovery

Prospect Biosystems' technology will provide rapid and valuable information to connect subcellular biology with biomarkers, and to identify additional pathway biomarkers and their network.

  • Fractionation and enrichment of a known pathway marker into well-defined specific subcellular locations for control and experimental samples
  • Calculation of the markerís relative % distribution among fractions
  • Determination of the fraction which shows the biggest difference in relative % distribution between control and experimental samples
  • Further separation of the defined fractions using 2DE or MUDPIT
  • Identification of additional differentially expressed proteins by mass spectrometry
  • Evaluation of those identified proteins which directly connect with the pathway
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